Monday, January 12, 2015

Mucoid Degeneration .

There will be accumulation of mucin like substance in an affected cell . This mucin is produced by the combination of protein and carbohydrate , termed as mucopolysaccharide and it is chiefly found in ground substance of connective tissue . The mucin may be either connective tissue mucin or epithelial mucin .

I . Connective tissue mucin -  This type of mucin is found where the connective tissue is present particularly in umbeluical cord , matrix of cartilage , vitreous humour of the eye and pulp of tooth . This type of mucin forms two types of ingredients like hyaluronic acid  and chondroitinn sulphuric acid . Under certain circumstances , as found in myxomas or myxoedema , there will be mucoid degeneration . it is also found in collagen disease , filariasis etc .


II .  Epithelial mucin – This is found in epithelial lining of respiratory tract , nasopharynx , gastro-intestinal tract , genito urinary tract . During inflammatory condition such as in common cold , large amount of mucin will produce .  Carcinoma of stomach , large bowel , breast ,etc may produce mucinous change . It may be called colloid carcinoma or mucnous carcinoma or mucoid carcinoman  .